LISTERIOSIS It can produce abortion and fetal or neonatal death. Infection of the human being with Listeria monocytogenes was identified in 1929 by Nyfeldt. The microorganism was first characterized, however, by Murray, Webb, and Swann in 1926 during an epizootic among rabbits and guinea pigs.
LISTERIOSIS Subsequently, the micro-organism has been identified as a cause of disease in fox, raccoon, goat, lemming, mouse, rat, hamster, pig, horse, cow.dog, domestic fowl and wild birds, and other animals. L. monocytogenes resembles Erysi-pelothrix rhuziopathiae and diphtheroids but can be differentiated from these bacteria by its motility (best at 20 to 30° C.), its specific antigenicity, and it’s animal pathogenicity. Incidence and Prevalence. In addition, the diverse manifestations of the dis-ease render it difficult to identify clinically. Epidemiology. person to person probably does not occur. Women can carry Listeria in the.
vagina and infection may be transmitted venereally. Whether or not a man can be an asymptomatic carrier of Listeria under other conditions is not known. Pathology and Pathogenesis. Lesions may develop in the liver, intestinal tract, skin, mucous membranes of the respiratory tract, lung, heart, spleen, lymph nodes, placenta, and brain. The fetus may be infected transplacentally through the umbilical vein, with the production of septicemia.
Clinical Manifestations. The onset may be abrupt or gradual, and the initial symptoms may be those of gastrointestinal or respiratory illness. Examination reveals manifestations of meningitis or encephalitis in varying degrees of severity. Febrile pharyngitis with cervical and generalized lymphadenopathy can be caused by Listeria and may be difficult to differentiate from infectious mononucleosis. In addition, lymph node enlargement associated only with conjunctivitis may occur.